Single nucleotide polymorphisms affect both cis- and trans-eQTLs
نویسندگان
چکیده
منابع مشابه
Single nucleotide polymorphisms affect both cis- and trans-eQTLs.
Single nucleotide polymorphisms (SNPs) between microarray probes and RNA targets can affect the performance of expression array by weakening the hybridization. In this paper, we examined the effect of the SNPs on Affymetrix GeneChip probe set summaries and the expression quantitative trait loci (eQTL) mapping results in two eQTL datasets, one from mouse and one from human. We showed that removi...
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ژورنال
عنوان ژورنال: Genomics
سال: 2009
ISSN: 0888-7543
DOI: 10.1016/j.ygeno.2009.01.011